She started me on the generic version of Plaquenil at 200 mg. I have had extreme nausea, diarrhea, stomach cramps, and intense vertigo. I began taking it on Thanksgiving day and still experience these side effects. What is hydroxychloroquine sulfate 200 mg used for Plaquenil safer than floroquinolones How immunosuppressant is hydroxychloroquine Methotrexate trexall and hydroxychloroquine plaquenil Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Yes, plaquenil can affect your liver. My doctor runs blood work at 6 month intervals to check on liver. I also get 6 month eye exams while on plaquenil. After gallbladder removal bile function is impaired which can cause digestive problems. It is also common for liver dysfunction to occur after gallbladder removal as extra work is put on the liver. To check liver function we recommend you get an ultrasound scan and/or liver function test. She cut my dose in half (100 mg) and that has partially helped the symptoms. A week ago I asked if there was anything we could do and she stated that this was the only treatment pill option. Can plaquenil cause liver problems Will you have Liver function test abnormal with Plaquenil., Does plaquenil elevate your liver enzymes? ProHealth. Plaquenil long term usHydroxychloroquine sulfate overdoseHydroxychloroquine and weight loss Liver Enzymes. The liver produces several enzymes involved in metabolism. Among them, the aminotransferases, also called the transaminases, ALT and AST, which function in protein metabolism, have particular diagnostic value, as they become elevated in several diseases, including those of the liver and gallbladder in addition to disorders of other tissues, including the heart and muscle. Elevated Liver Enzymes and the Gallbladder Healthfully. Things you must know if you don’t have a gallbladder.. Warning Signs and Symptoms of The Liver Disease that.. Find information about common, infrequent and rare side effects of Plaquenil Oral. With regard to plaquenil and Eye tests, the eye issues produced by sarcoidosis such as uveitis are quite different from the potential for retinal toxicity which can occur with Plaquenil. The tests are Field Tests for peripheral vision. Retinal toxicity of plaquenil can cause tunnel vision. This is why the eye tests are performed. Issues with the immune system may cause attacks on the liver causing Primary biliary cirrhosis; Autoimmune hepatitis; Primary sclerosing cholangitis 1,2 Fatty liver. Alcoholic liver disease ALD-specific early symptoms are abdominal pain, feeling sick, fatigue, feeling unwell, and decrease in appetites. Specific late symptoms are jaundice, swelling of extremities, fever, and itchy skin.