This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil related toxicity Quinine chloroquine side effects A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. There have been no previous reports of this adverse reaction in leprosy patients receiving chloroquine for treatment of reactions. The author recommends that chloroquine be used with caution especially in patients with seizures. Jul 30, 2019 These side effects were seen most often in patients receiving large doses for treatment of lupus or rheumatoid arthritis; however, such reactions have been noted in patients taking therapeutic doses for short periods. Symptoms often resolved over time with a reduction of the dose or discontinuation of chloroquine. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine in lepra reaction Chloroquine alternatives - Answers on HealthTap, Seizures following chloroquine treatment of type II lepra. What does a plaquenil rash look likeHydroxychloroquine liver function testsChloroquine solubility dmsoMylan hydroxychloroquine side effectsPlaquenil fact sheet Jul 12, 2018 Q. 10 Reversal lepra reaction shown no response to A Cloafazimine B Chloroquine C Glucocorticoids D Thalidomide Q. 10 Reversal lepra reaction shown no response to A Cloafazimine B Chloroquine C Glucocorticoids D Thalidomide Ans. D Explanation D. i.e. Thalidomide Appearance of new skin lesions or signs of inflammation e.g. redness and swelling etc. in prevous lesions, neuritis e.g. nerve pain and low grade fever in borderline forms of leprosy suggest the diagnosis of Jopling's type I. Lepra Reaction And Erythma Nodosum Leprosum -. Chloroquine Side Effects Common, Severe, Long Term -. Treatment of lepra reactions - WHO. Without treatment, type 2 lepra reactions continue for about 2 weeks then settle down. Recurrences are frequent. Untreated type 2 lepra reactions can result in renal failure requiring dialysis, liver failure requiring transplantation, blindness, and/or long-term inflammation of the testicles. Lucio phenomenon The following drug is not used for the treatment of type II lepra reaction a Chloroquin b Thalidomide c Cyclosporine d Corticosteroids Correct answer c Cyclosporine Drugs used in treatment of type II lepra reaction are NSAID’s Thalidomide Chloroquine Clofazimine Corticosteroids Parenteral antimony Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.