He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Echocardiography revealed a left ventricular ejection fraction of 25%, with diffuse hypokinesis. Chloroquine and proguanil in pregnancy Best way to monitor patients for plaquenil Oh Serenity, I once tried to go OFF plaquenil before taking Isoniazid to lessen the burden on my liver. It was a very bad idea. I got the symptoms Lynnwood described going off the plaquenil and had such bad heart problems that I went right back on. And I was only off for a day or so. My legs swelled up really bad and I got edema everywhere. Discussion. Echocardiographic findings of HCQ cardiomyopathy are variable, ranging from increased ventricular wall thickness with or without dilatation and systolic or diastolic dysfunction and can mimic other causes of myocardial dysfunction in SLE patients such as myocarditis, amyloidosis, ischemic heart disease, other toxic drugs eg, amiodarone, and rarely, Fabry disease or other storage. Heart problems like heart failure and a certain abnormal heartbeat prolonged QT interval have happened with Plaquenil hydroxychloroquine. Sometimes, these heart problems have been deadly. Sometimes, these heart problems have been deadly. The differential diagnosis for new onset non-ischemic cardiomyopathy in this patient included inflammatory cardiomyopathy, viral myocarditis, sarcoidosis, amyloidosis, hemochromatosis, Fabry's disease and HCQ toxicity. Coronary angiography demonstrated non-obstructive coronary disease. Treatment was initiated with guideline directed medical therapy, and patient clinically improved. Plaquenil and heart issues Rapid Heartbeat with Plaquenil - Lupus - MedHelp, Hydroxychloroquine-Induced Cardiomyopathy Circulation Heart Failure Plaquenil grapefruitCan you take plaquenil and xanax togetherChloroquine translationIcd code for plaquenil useConditions to take plaquenil Plaquenil and Coronary heart disease - from FDA reports Summary Coronary heart disease is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Vioxx, and have Osteoporosis. Will you have Coronary heart disease with Plaquenil.. Plaquenil Indications, Side Effects, Warnings -. What Conditions does Plaquenil Treat? - WebMD. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Though serious heart muscle disease is not commonly caused by lupus, heart failure can occur if your heart does not have the strength to pump enough blood to the different tissues and organs. Endocarditis. The endocardium is the tissue that lines the inner walls of your heart and the valves that separate the heart’s different chambers.