Answer: Both Warfarin (brand name - and Plavix (generic - clopidogrel bisulfate) are considered blood thinners, but they are very different drugs with different actions. Warfarin works by counteracting Vitamin K in the plasma of the blood. Vitamin K is key in the coagulation pathways responsible for the clotting of blood, and with less activity of Vitamin K blood takes longer to clot. Too little, as well as too much warfarin can be dangerous. If taking a dose that is ineffective, clot formation is not adequately prevented and the problem you are trying to treat or prevent may very well occur. Taking too much warfarin raises the risk of bleeding, especially in the gastrointestinal tract and, in the elderly, the brain. People taking this drug must have their blood monitored to measure the time it takes to clot, which can result in frequent adjustments of their dose. Plasma warfarin concentrations and warfarin effects may be increased. Com, Lasix (furosemide) may displace warfarin from plasma protein binding sites. This interaction is characterized as minor clinical importance. However, everything else being the same, and that she did not confuse her Lasix (furosemide) with Coumadin and take more Coumadin than thought, then this interaction may have contributed to the increased inr. In any case, this is too high and if she is bleeding, or altered mental status or paralysis, she should be sent to the hospital for evaluation and treatment. However if she is stable, hold the Coumadin and retest her inr. She can resume taking her dose when the inr is less than 5.0. Buy prednisone for dogs Buy kamagra online australia Can Lasix affect INR Coumadin level? My 84 year old mother is on Coumadin theropy has st judes valve it has been in the INR targeted range of 2.5-3.5 but today it was 8.0.do home testing and checked it twice. WARNINGS Furosemide is a very potent medication. Using too much of this drug can lead to serious water and salt/mineral loss. Therefore, it is important that you are closely monitored by your. Ther Drug Monit. 1997 Jun;193361-3. Decreased hypoprothrombinemic effect of warfarin associated with furosemide. Laizure SC1, Madlock L, Cyr M, Self T. HCTZ (hydrochlorothiazide) is a very weak diuretic that is very good for Hypertension and sometimes, the first drug used. Lasix (furosemide) is a stronger diuretic better used for congestive heart failure than for hypertension. Read more Furosemide is a potent diuretic which increases dramatically urine output in most patients. It is most frequently used in patients who are fluid overloaded such as in congestive heart failure. Potassium , sodium and magnesium can be lost in excess with the use of Furosemide and must be closely monitored. It is much stronger than other diuretics used for Coumadin (warfarin) is an anticoagulant that works to block production of some of the building blocks used in blod clotting. It needs to be monitored regularly due to the fact that the levels can very in the body, affected by foods you eat, interactions with other medications, and your own metabolism. Read more See 3 more doctor answers Good hydration status and less alcohol (which is dehydrating) lead to more favorable outcome profiles in those with portal vein thrombosis. Alcohol may also raise your risk of bleeding in the setting of coumadin (warfarin). Read more See 1 more doctor answer cozaar (losartan) or an ACE inhibitor is better for diabetes. I mentioned in an earlier Small Talk thread that Jerry's feet, ankles & legs had been swelling and he started on 1 or 2 Lasix a day. Lasix and coumadin Lasix and coumadin - Answers on HealthTap, Lasix Oral Uses, Side Effects, Interactions, Pictures. How can i purchase valtrexAzithromycin dizzinessBuy generic viagra Feb 23, 2009. Jill, Coumadin is the trade name for warfarin, an oral anticoagulant. Lasix decreases swelling only by making the kidneys produce more. Rat Poison - CHI Health Better You Blog. Decreased hypoprothrombinemic effect of warfarin associated with.. The effect of furosemide and bumetanide on warfarin metabolism and.. Expert Opin Drug Saf. 2012 May;113375-80. doi 10.1517/14740338.2012.624091. Epub 2011 Sep 30. Effect of oral diuretics on chronic warfarin therapy a. The use of warfarin is considered "full anticoagulation" and is felt to be more effective a higher level than other oral blood thinners. Plavix is a drug known as an anti-platelet drug. COUMADIN crystalline warfarin sodium is an anticoagulant which acts by. COUMADIN for Injection is supplied as a sterile, lyophilized powder, which, after.