The primary use of trazodone is the treatment of major depression. Data from open and double-blind trials suggest the antidepressant efficacy of trazodone is comparable to that of amitriptyline, doxepin, and mianserin. Also, trazodone showed anxiolytic properties, low cardiotoxicity, and relatively mild side effects. Because trazodone has minimal anticholinergic activity, it was especially welcomed as a treatment for geriatric patients with depression when it first became available. Three double-blind studies reported trazodone has antidepressant efficacy similar to that of other antidepressants in geriatric patients. However, a side effect of trazodone, orthostatic hypotension, which may cause dizziness and increase the risk of falling, can have devastating consequences for elderly patients; thus, this side effect, along with sedation, often makes trazodone less acceptable for this population, compared with newer compounds that share its lack of anticholinergic activity but not the rest of its side-effect profile. Still, trazodone is often helpful for geriatric patients with depression who have severe agitation and insomnia. It can be used alone or in combination with mood stabilizers such as lithium or valproate (e.g., Depakote). It has been an FDA approved treatment for schizophrenia since 2010 and for treating depressive episodes in adults with bipolar I disorder since 2013, and is frequently prescribed for the treatment of major depressive disorder (MDD). It received regulatory approval in the United Kingdom in September 2014. In October 2014, NHS Scotland advised use of lurasidone for schizophrenic adults who have not seen improvements with previous antipsychotics due to problems that arise from weight gain or changes in metabolic pathways when taking other medications. It received approval by the European Medicines Agency on 24 January 2014. It was launched in Canada for the treatment of schizophrenia in September 2012, Health Canada giving their Summary Basis of Decision (SBD) as favourable on 15 October 2012. In a 2013 study in a comparison of 15 antipsychotic drugs in effectiveness in treating schizophrenic symptoms, lurasidone demonstrated mild effectiveness. Purchase generic propecia Buy propecia cream How to buy xenical online Aspirin learn about side effects, dosage, special precautions, and more on MedlinePlus Lists the various brand names available for medicines containing metoprolol. Find information on metoprolol use, treatment, drug class and molecular formula. Metoprolol succinate 47.5mg equivalent to Metoprolol tartrate 50mg/tablet & Metoprolol succinate 95mg equivalent to Metoprolol tartrate 100mg/tablet Tablet Drug International Ltd. Information about drug Metoprolol includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. To view the price of the drug, click on the brand name. The generic Metoprolol is manufactured by one company. Medindia's drug directory has currently 90 Brands of Metoprolol listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies. India is the world's capital for quality medicines, be it pharmaceutical formulations, herbal medicines or nutraceuticals. Our Pharma Division deals only with the best, GMP certified generics and branded medication for the export market. Carvedilol and metoprolol are both beta blockers, but differ mainly in their selectivity of which beta-receptors they block. Carvedilol blocks both alpha and beta receptors and metoprolol is more cardioselective, that is, more selective to the heart. Depending on the manufacturers, the trade names of these medications differ from country to country. Both carvedilol and metoprolol are used to treat hypertension and cardiac conditions such as angina or congestive cardiac failure. They work by blocking beta receptors around the heart which prevents the action of adrenaline and noradrenaline, the fight or flight hormones. This slows the heart down and, in turn, reduces the pressure both on the heart and blood pressure. Unlike metoprolol, carvedilol also has some blocking action on alpha receptors, which causes widening of the blood vessels and less resistance, thus also lowering blood pressure. 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REDDY'S Lurasidone / lj ʊəˈr æ s ɪ d oʊ n /; trade name Latuda is an atypical antipsychotic developed by Dainippon Sumitomo Pharma and marketed by Sunovion in the U. S.