Ongoing monitoring of blood counts, liver and kidney function is also required. Prescribed for Acute Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Rheumatoid Arthritis, Psoriatic Arthritis, Solid Tumors, Small Cell Lung Cancer, Systemic Sclerosis, Neoplastic Diseases, Trophoblastic Disease, Osteosarcoma, Non-Small Cell Lung Cancer, Non-Hodgkin's Lymphoma, Psoriasis, Mycosis Fungoides, Dermatomyositis, Breast Cancer, Choriocarcinoma, Meningeal Leukemia, Graft-versus-host disease, Head and Neck Cancer, Juvenile Idiopathic Arthritis, Lymphoma. Hydroxychloroquine kidney side effects Chloroquine aralen primaquine metronidazole flagyl nitrofurantoin furadantin Does plaquenil work without methotrexate Early plaquenil toxicity oct Compare Methotrexate vs Prednisone head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Prednisone rated 7.7/10 in overall patient satisfaction. Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in antigen presentation or effects on the innate immune system. Both were controllling RA very well, but Plaquenil was also irritating scalp very badly which is why we switched to Arava. Arava started blistering & peeling skin off of fingers & toes lovely. It also helped RA. I went back on the Plaquenil about the time of my first post, but in two days had horribly red,itchy, irritated scalp. Tried first MTX this morning. " Prednisone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. May also be prescribed off label for Bladder Cancer, Acute Nonlymphocytic Leukemia, Soft Tissue Sarcoma, Scleroderma, Pityriasis rubra pilaris, Pemphigus, Pemphigoid, Pancreatic Cancer, Ovarian Cancer, Mantle Cell Lymphoma, Brain Tumor, Bullous Pemphigoid, Cervical Cancer, Cogan's Syndrome, Colorectal Cancer, Ectopic Pregnancy, Eczema, Esophageal Carcinoma, Gastric Cancer, Hodgkin's Lymphoma, Uveitis. Whichhis worse plaquenil or methotrexate Plaquenil and brainfog I just started on the. - LUPUS UK, Rheumatoid Arthritis Treatment Options Johns Hopkins. Hydroxychloroquine what is it used for Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Compare Plaquenil vs Methotrexate -. Methotrexate vs Plaquenil? -. Methotrexate vs Plaquenil Comparison -. Hi in case you see this - its been two years and I successfully cut my plaquenil and methotrexate in half with no return of symptoms. One week I forgot to take the meth and got a mild return of symptoms - scared the hell out of me but just resuming the same low dose squashed it. Now I'm trying to decide which is my next target. Methotrexate vs plaquenil side effects long term and short term I was recently diagnosed with an autoimmune disease that mainly fuses my joints together, but causes severe pain and fatigue. The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. Methotrexate can make a person fatigued the day after a dose, and it can cause gastrointestinal upset. In general, methotrexate is very well tolerated; however, one should not get pregnant while taking this drug, due to known toxicity to a developing fetus.