While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I was on this hydroxychloroquine for 6 months and then suddenly developed severe itching (burning like sensation, worse than any itch I have ever had) and rash that went from my neck to my feet. Chloroquine huh7 Chloroquine dosage for prevention of malaria Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. All since then I've been tested and diagnosed. Today my rheumy decided to go ahead and prescribe plaquenil. My main issues are joint, muscle and tendon pain/inflammation,As well as fatigue. Besides my possible heart and lung involvement My doc said plaquenil will help with the pain and inflammation. Will it help with the fatigue? I'm not completely pain free, but it's a lot better than it was. I've been on plaquenil since mid June I have had a lot of stress in my life so I can't determine what is causing what. Not seeing any improvements with pain but I just went to 0 prednisone 3 weeks ago. said give it a few months and if I don't see any improvement I might as well go off of it. Wanted to let you know that I was on plaquenil for about three years and I told my RA doctor that my fatigue was worse. Hi everyone, I am wondering if anyone has had a problem with fatigue while on Plaquenil. At first, I was nauseous for a week or so, which the dr. After the nausea went away it seemed like my pain got worse for a week or so, and then it gradually got better. I am also bothered with stomach cramps and mild diarrhea. How does plaquenil help with fatigue Hydroxychloroquine Plaquenil, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Apo-hydroxychloroquine for swellingUses for hydroxychloroquine Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Ask the Expert Plaquenil and Sjögren’s. Does plaquenil help with fatigue. DailyStrength. Things that Changed My Life with Lupus Fatigue, Part 3. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Last August I decided to retire due to fatigue and joint pain. Plaquenil does relieve much of the fatigue. As for the joint pain, still a problem. Yes, depression is an issue, still is. The form of meditation I practice is called Mindfulness Based Stress Reduction and daily practicing helps relieve the symptoms of depression.