One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil dose for malaria prevention Plaquenil anxiety Plaquenil or hydroxychloroquine HCQ is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid The Risk of Retinal Toxicity with Plaquenil YOUR CREDIBLE SJÖGREN'S RESOURCE Hydroxychloroquine overdose is infrequently reported and the majority of recommendations come from the greater experience with chloroquine poisoning. We report two cases of massive hydroxychloroquine poisoning 20 g in each case, both of which received advanced cardiac life support and a treatment regimen consisting of sodium bicarbonate, adrenaline and potassium. Abstract Hydroxychloroquine poisoning has rarely been reported in the literature, with only 18 cases being found on searching the literature. In this paper, we report a case that occurred in Hong Kong, and we make recommendations for emergency management of hydroxychloroquine overdose based on our and other's experience. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Hydroxychloroquine overdose toxicokinetics and management New Screening Guidelines for Hydroxychloroquine Toxicity, Survival after Massive Hydroxychloroquine Overdose - N. Gunja. Plaquenil how to buyPlaquenil kidney side effects Background The management and toxicokinetics of hydroxychloroquine overdose are poorly described. Case Report We report a case of an 18-year-old girl who ingested 20 g of hydroxychloroquine. She developed marked hypokalemia, hypotension, and ventricular tachyarrhythmias but survived with treatment including intubation, adrenaline infusion, high-dose diazepam, and aggressive potassium replacement. Hydroxychloroquine Overdose Toxicokinetics and Management.. Hydroxychloroquine overdose case report and recommendations.. Recommendations on Screening for Chloroquine and.. Quick treatment of hypotension, gastric decontamination, continuous long-term cardiac monitoring, and treatment of arrhythmias are the cornerstones of hydroxychloroquine overdose management. Hydroxychloroquine is a 4-aminoquinoline derivative prepared by beta hydroxylation of chloroquine. It is used in the treatment of malaria, rheumatoid arthritis, and lupus erythematosus, and marketed under the name Plaquenil Sanofi Pharmaceuticals, New York, NY. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex updated, Cerner Multum™ updated, Wolters Kluwer™ updated.