It seems to me the cure is worse then the condition! Hi im starting plaquenil 200mg twice a day was wondering how far apart should the dose, be and best times to take it ,what are some of the side effects anyone has had and how long did it take to start working thank u You take plaquenil twice a day, approximately 12 hours apart. Plaquenil corneal toxicity Hydroxychloroquine pulmonary fibrosis Hydroxychloroquine with lamotrigine with oxycodone Hydroxychloroquine high dose Take this medicine with meals or milk to lessen stomach upset, unless otherwise directed by your doctor. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. For patients taking hydroxychloroquine to prevent malaria I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. I have found that for me i can't take my Plaquenil before bed as it makes me anxious and makes it difficult to sleep. I work overnights, so I take it before i go to work, then by the time I get home I am able to sleep ok. I always take it with food though, as it makes me nauseous otherwise. You can take it with food if it upsets your stomach. The most common side effect is mild nausea and occasional stomach cramps. Best way to take plaquenil Taking Plaquenil for Rheumatoid Arthritis, Had to stop taking Plaquenil - 1h chloroquine binding biochemistry and biophysicsItchiness side effect of chloroquine Plaquenil is a slow acting drug and most people dont notice any difference in the way they feel for at least a month. It takes up to 3 months to build up in your body and actually start to make a difference in your blood work and symptoms. Most rheumy's will give plaquenil along with prednisone to boost/quicken the anti-inflamitory process. I'm afraid to take Plaquenil DailyStrength. Best time to take Plaquenil? rheumatoid. Anyone else afraid to take plaquenil. lupus - reddit. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. Protecting your eyesight when taking Plaquenil With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. Ive just been diagnosed and put on 400mg of Plaquenil but now I feel worse. I find the best way is to try and identify the foods or food-groups that trigger my.