It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil medicine Does plaquenil effect the brain fog One of the problems with Plaquenil is that because it's so slow to act, the improvements are also slow and subtle. So most people don't realize that they've improved until they STOP taking it. I've been on it twice, along with Atabrine another antimalarial. In my case, it never worked so I didn't notice a change. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except. The recommended initial dosage of hydroxychloroquine Plaquenil for the treatment of lupus erythematosus is 400 mg once or twice daily. The recommended maintenance dose range of hydroxychloroquine Plaquenil for the treatment of lupus erythematosus is 200 to 400 mg daily. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. What exactly does plaquenil do Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Foods to Avoid When Taking Plaquenil Oral Can aspirin interact badly with plaquenil Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol.. What exactly does Plaquenil do. - Sjogren's World. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. though it is not known exactly how. All information contained within the Johns Hopkins Lupus Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. What are everyone's thought on Plaquenil? Good drug for Lyme, bad drug for Lyme? What does it do exactly and how does it effectively reduce risk of relapse? Does it accumulate in tissues? Is it toxic? So far I read it alkalizes inside of cells. Makes intracellular antibiotics work better, and blocks some Borrelia enzymes.