It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Does allwell cover plaquenil Chloroquine myopathy Can i take cbd with hydroxychloroquine Plaquenil how long does it take to work I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the plaquenil. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil how long does it take to work Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly? Plaquenil pregnancy class It may take up to six months before the full benefits of Plaquenil are realized. Dosage The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil -. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Indicates that you can expect to see some results after a month or two of taking hydroxychloroquine, but in order to get the full benefits you will need to take the medication for at least six months. That can help you realize how much benefit you’re going to actually get from the drug. Flesh colored itchy rash on top of feet and inside ankle. I do take plaquenil hydroxychloroquine 400mg daily fo more Flesh colored itchy rash on top of feet and inside ankle. I do take plaquenil hydroxychloroquine 400mg daily for ra. Havent changed soaps, detergents, etc. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first even when your symptoms improve to help keep the disease under control.