It typically happens in the evening or nighttime hours when you're sitting or lying down. Restless legs syndrome, also known as Willis-Ekbom disease, can begin at any age and generally worsens as you age. It can disrupt sleep, which interferes with daily activities. Chloroquine aralen drug card Areas with chloroquine or mefloquine resistance Hydroxychloroquine sulfate drug class Jun 25, 2013 hydroxychloroquine is the generic form of Plaquenil but the side effects are the same. My thigh muscles are so sore I can hardly walk, sit or stand. Stairs are a TRUE challenge. I have to struggle up and down taking only one step at a time using only one leg at a time. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. I too have that 'heavy' feeling in my legs where it feels almost as if you won't be able to pick up your feet and so tend to shuffle. Going up steps is very difficult as some days it is easier to move one leg than the other. I don't, however, have to be standing a lot for this to happen. Medications also help many people with symptoms as abnormal, unpleasant sensations in their legs or feet. They do, however, consistently describe the desire to move their legs. Sometimes, symptoms disappear for periods of time, then come back. Simple self-care steps and lifestyle changes may help relieve symptoms. The sensations, which generally occur within the limb rather than on the skin, are described as: usually don't describe the condition as a muscle cramp or numbness. Plaquenil heavy legs Nighttime Leg Cramps Meds That Hurt, Meds That Help - GoodRx, Hydroxychloroquine Oral Route Description and Brand. Reticulocytes chloroquineMacular oct for plaquenilSickle cell disease hydroxychloroquine thrombosis After about 4 day of being off Plaquenil I quickly realized that it in deed was helping. I was at work and at the end of my day I proceeded to walk to my car and could barley raise my legs to walk. I legs felt so heavy, the fatigue was at an all time high and the joint and muscle pain was unbearable. Stopping plaquenil. DailyStrength. Heavy Legs feeling - Lupus - Inspire. How to Avoid Having Heavy Legs & Swelling of Ankles.. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. I have been on 400 mg daily of Plaquenil, last week my doctor took me off of it ue to increase in the pain I had been having in lower back and unbelievable pain in my left leg and especially the extreme pain in the heel of my left foot. It was becoming painful to walk. After 5 days of stopping pain was 80% better. This was twice cleared up with heavy doses of antibiotics and Cortisone. However my rheumatologist took me off all arthritis drugs and we added them back little by little. When plaquenil was finally included with the other drugs again, it took about three days and my My face started swelling and the rash and and itching.