I know I had never heard of it until my rheumatologist said that is what I have...along w/osteoarthritis and fibromyalgia. My blood tests are negative for RF but my CRP test was above normal. Ai Yi Yi Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells (these are messengers for your immune system, if you will) from interacting with your T-Cells (a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders). So, he started me on 400 mg of Plaquenil a day and he just upped it to 600 mg a day. As I said previously, my Rheumatologist now says it is inflammatory osteoarthrits. Why am I taking Plaquenil, which does help tremedously BTW, if I don't have RA or Lupus. This "dendritic deactivation" (I made that phrase up) helps reduce your immune system being silly and inflaming your joints. Can hydroxychloroquine cause vision changes Can i take plaquenil at the same time as metformin Plaquenil and valley fever Plaquenil and Knee joint replacement - a study from real-world data. Summary Knee joint replacement is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Enbrel, and have Pain. Hi all. I have been on Orencia since July 2006 and Plaquenil before that. I have noticed for a while that immediately after my treatment of IV Orencia my eyesight became a bit blurred where I could not see fine print with or without my wasn't really troublesome to me, but I did happen to mention it to my Rheumatologist at my last month visit. Sep 18, 2007 Answer. Plaquenil does not need to be stopped for surgery so it can be restarted after the procedure. Although in studies Celebrex does not cause increased bleeding, unilke other older NSAIDs, some surgeons still advise to stop it to be safe. In general, Celebrex can be restarted the day after the procedure once the risk of bleeding is over. My sister was dx'd with Inflammatory Arthritis and Plaquenil sent her into remission some years ago now. I also take meds for high bp, asthma and high cholesterol. Plaquenil and knee replacement Total Knee Arthroplasty Considerations in Rheumatoid Arthritis, Plaquenil and Orencia" Osteoarthritis Community - Support Group Risk of plaquenil toxicityChloroquine phosphate for lupusPlaquenil and fibromyalgiaHydroxychloroquine malaria prophylaxis doseChloroquine methemoglobin Currently on plaquenil and tramadol and have had no relief. My main concern is my joints are breaking down. Knees and ankles. Had a knee replacement at the age of 28 and I am now 40 and looking at needing ankle fusions. Stills Disease Mayo Clinic Connect. How long to be off Celebrex adn Plaquenil for a Surgery.. Lupus and Joint Replacement Surgery What You Should Know. Comment Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Nov 29, 2010 Does anyone know why you had to stop Plaquenil before surgery? I'm just curious because I had a partial knee replacement when I was on Plaquenil and wasn't advised to stop it - or any of the other meds I was on. Take care - Scottie Nov 26, 2014 Platelet rich plasma PRP is a relatively new therapy that has been successfully used in the fields of sports medicine and trauma. 1 PRP therapy is the use of a patient’s own blood plasma that has been enriched with his or her platelets and injected into an area of damaged tissue.