They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Chloroquine or prophylaxis Msds chloroquine phosphate Chloroquine autophagy inducer It tends to weaken it. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Machanic on does hydroxychloroquine suppress the immune system been shown to affect the immune system. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does plaquenil weaken your immune system Coronavirus and Arthritis What You Need to Know, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Why is the drug hydroxychloroquineChloroquine 150 mgCan plaquenil cause a positive nicotine urine test Aug 02, 2010 Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. No, his immune system should not be forever compromised. Do either hydroxychol/Plaquenil put you at risk for greater.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. What Is Plaquenil? - American Academy of Ophthalmology. Plaquenil and Immune system disorder - from FDA reports Summary Immune system disorder is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Howdy LadyDi, sorry you are having problems. Plaquenil is what is call an immune modifier. It is not a immune suppressant. Originally it was used to prevent Malaria. Then it was discovered to be effective for the treatment of Lupus. Plaquenil has the least amount of side affects in treating auto immune disorders. Feb 19, 2020 Immune system disorders Urticaria, angioedema, bronchospasm Metabolism and nutrition disorders Decreased appetite, hypoglycemia, porphyria, weight decreased. Musculoskeletal and connective tissue disorders Sensorimotor disorder, skeletal muscle myopathy or neuromyopathy leading to progressive weakness and atrophy of proximal muscle groups, depression of tendon reflexes and abnormal nerve conduction.