Sd-oct and plaquenil toxicity

Discussion in 'Chloroquine 150 Mg' started by Sole, 09-Mar-2020.

  1. hidden2006 Guest

    Sd-oct and plaquenil toxicity

    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. In analyzing SD-OCT, it is imperative to pay special attention to the outer retina Figure 3. Thinning of the photoreceptor layer, ellipsoid layer, outer nuclear layer, and RPE can be among the earliest signs of hydroxychloroquine toxicity. 4 These changes often occur in the parafoveal area, although they can be more peripheral in Asian patients.

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Sd-oct and plaquenil toxicity

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  5. Apr 30, 2013 SD-OCT scan from a 44-year-old woman with bilateral plaquenil toxicity. There is damage visible in the outer retina in a perifoveal distribution. Related files

    • Plaquenil Toxicity - Retina Image Bank.
    • Retina Today - Imaging in Hydroxychloroquine Toxicity..
    • Retinal Physician - Hydroxychloroquine Maculopathy An..

    Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so. Table 3 demonstrates that fields, mfERG, FAF, and SD-OCT can all show damage at a relatively early stage of hydroxychloroquine toxicity, but it is not predicable as to which test will be most definitive for any given individual. This makes a strong argument for using more than 1 modality routinely or at least for bringing in multiple modalities. SD-OCT and AO detected abnormalities that correlate topographically with visual field loss from hydroxychloroquine toxicity as demonstrated by HVF 10-2 and may be useful in the detection of subclinical abnormalities that precede symptoms or objective visual field loss.

  6. Morgentau Well-Known Member

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. DermatologyNotes OCR Epidermis Integumentary System Gov Plaquinel changes hair color?" Lupus Community - Support.
  7. aoc1 Guest

    Chloroquine Phosphate - WebMD How to use Chloroquine Phosphate. Take this medication by mouth, usually with food to prevent stomach upset, exactly as directed by your doctor. Daily or weekly dosing, dosage amount, and length.

    Breakthrough Chloroquine phosphate shows efficacy in COVID.