Long-term progression of hydroxychloroquine retinopathy off the drug

Discussion in 'Cheap Chloroquine' started by vovan003, 04-Mar-2020.

  1. Yurka User

    Long-term progression of hydroxychloroquine retinopathy off the drug


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    Hydroxychloroquine and CQ retinopathy are not reversible, and cellular damage may progress even after the drugs are stopped. When retinopathy is not recognized until a bull’seye appears, the disease can progress for years, often with foveal thinning and an eventual loss of visual acuity. Chloroquine retinopathy, is a form of toxic retinopathy caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. Data are available on the presenting features and long-term follow -up of patients with hydro xychloroquine retinopathy, making it diffic ult to surmise the clinic al course of patients

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Long-term progression of hydroxychloroquine retinopathy off the drug

    AMERICAN COLLEGE OF RHEUMATOLOGY, Chloroquine retinopathy - Wikipedia

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  6. Later damage, as toxicity evolved to a severe stage, was diffuse across most of the macula. If the drug was stopped at an early or moderate stage, progression was limited to the first year and occurred diffusely without parafoveal localization. CONCLUSIONS Hydroxychloroquine retinopathy primarily involves outer retina photoreceptors.

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    Baseline and periodic screening for retinopathy is necessary for rheumatologic uses and in long-term therapy eg, 1 to 5 years depending on patient risk factors AAO Marmor 2016; Travassos 2019. Tolerability GI upset nausea, vomiting, diarrhea is a common adverse effect. Dividing doses, taking with food, and, if appropriate, gradual dose escalation in treating rheumatologic diseases may improve tolerability Wallace 2019. Nevertheless, retinopathy begins to appear with long-term use, and retinopathy is serious insofar as there is no known treatment. It can progress for a year or more after stopping the drug and, if not recognized early at the point of screening, it can lead to functional blindness. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1

     
  7. tarog New Member

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. When does the plaquenil kick in? DailyStrength Hydroxychloroquine how long to take effect? - NRAS How long until Plaquenil started working?
     
  8. fsplen User

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. DRUG-NUTRIENT DEPLETION AND INTERACTION CHARTS Plaquenil and Vitamin d drug interactions - eHealthMe Plaquenil Oral Interactions with Other Medication
     
  9. Den2006 Guest

    Plaquenil Oral Tablet Drug Information, Side Effects, Faqs HYDROXYCHLOROQUINE hye drox ee KLOR oh kwin is used to treat rheumatoid arthritis and systemic lupus erythematosus. It is also used to treat malaria. Similar Generic Drugs Hydroxychloroquine Oral tablet

    Plaquenil Uses, Dosage & Side Effects -