Amiodarone, an antiarrhythmic, is the most common cause of corneal verticillata, followed by chloroquine, hydroxychloroquine, indomethacin, and phenothiazines. A comprehensive list of systemic drugs associated with corneal verticillata is given in . Can plaquenil cause liver damage Does hair loss differ when it is due to plaquenil Cornea verticillata also called vortex keratopathy, whorl keratopathy, or Fleischer vortex describes a whorl-like pattern of golden brown or gray opacities in the cornea. It is termed cornea verticillata from the Latin noun “verticillus,” meaning “whorl”. Chloroquine and hydroxychloroquine can pass through the placenta, but do not appear to cause harm to the baby and likely is beneficial to both mother and baby by an improved pregnancy outcome. Both drugs are excreted in breast milk. Studies of pregnant mice revealed that the drug accumulates in the fetal retina. Name /bks_53161_deglins_md_disk/hydroxychloroquine 03/07/2014 AM Plate # 0-Composite pg 1 # 1 PDF Page #1 Canadian drug name. Genetic Implication. The deposits typically resolve with discontinuation of the responsible agents. It is unusual for these deposits to result in reduction of visual acuity or ocular symptoms, although this has occurred in some patients. Hydroxychloroquine keratopathy Hydroxychloroquine sulfate and Abstral drug interaction., Chloroquine And Hydroxychloroquine Toxicity - Abstract. How effective is plaquenil for scarring alopeciaFinancial assistance for hydroxychloroquineDoes hydroxychloroquine have renal toxicityIs chloroquine a quinoloneMethotrexate plaquenil sulfasalazine Apr 26, 2015 It commonly causes a whorl keratopathy or vortex keratopathy as seen above for side effects of plaquenil, which are deposits on the cornea front surface of the eye. As mentioned earlier, this does not usually affect the vision, but some patients report a green halo in their vision. Systemic Medications that have Ocular. - Dr. Farah Lakhani. Avoiduse Pedi Long-termuse hydroxychloroquine hye-drox.. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. Hydroxychloroquine Keratopathy - Example #1 Hydroxychloroquine rarely can be seen as deposits in the basal epithelium of the cornea as shown in this image white arrows. This occurs commonly in patients taking chloroquine, but rarely in patients taking hydroxychloroquine. Hydroxychloroquine keratopathy presents as an intraepithelial deposit. The deposits may take the form of whirls, linear opacities, or punctate lesions. Ciliary body dysfunction can be detected by poor near vision. Symptoms. In the initial stages of hydroxycloroquine toxicity, patients are often asymptomatic. BACKGROUND Vortex keratopathy, arising as a side effect of several medications, is characterized by golden-brown deposits in the cornea. METHODS A 41-year-old woman treated for sarcoidosis with hydroxychloroquine therapy and suffering from vortex keratopathy was examined by in vivo confocal microscopy. Scans of both corneas were performed.