She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Hydroxychloroquine and neutropenia Chloroquine inhibits autophagic flux by decreasing autophagosome lysosome fusion Plaquenil vs benlysta lupus The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina. Well, that nov post here recommended a visual field test every 6 months, and a computerised 3d retina scan every year - She said she had been on plaquenil for 12 years, regularly having these tests inc I guess doing her amsler grids and she felt they were really important, but so far she had no eye problems. After the surgery, the blind area was more noticeable because my sight in that eye was so much clearer,” she says. “The surgeon sent me to a retina specialist, who recommended that I cut down my dose of Plaquenil. Finally, my rheumatologist recommended that I stop taking the drug altogether.” Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. I need an eye exam for plaquenil retinal function Hydroxychloroquine Plaquenil Toxicity and Recommendations., Plaquenil/Hydroxychloroquine - which eye tests do. - HealthUnlocked Ufo sign plaquenilHydroxychloroquine what herbs to takeHydroxychloroquine for dermatomyositisChloroquine ineffective on exoPlaquenil manufacturer covis Lyons emphasizes the importance of annual screening and says that, although annual screening is recommended for everyone taking Plaquenil, it is imperative for people who have been taking the medication for more than 10 years, who have a higher incidence of retinal toxicity. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. Protecting your eyesight when taking Plaquenil Lupus.. Protecting your eyesight when taking Plaquenil Lupus Foundation of.. Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening. Alot of the concerns are related to the problems caused by chloroquine, the predecesor to hydroxychloroquine Plaquenil. It was much more toxic to the retina and much more likely to cause permanent visual problems. Hydroxychloroquine, on the other hand, is much less toxic to the retina and there have been fewer reported eye problems. Recently, specialists have announced new guidelines for Plaquenil screenings because of associated retinal problems while taking Plaquenil. Also, the technology for detecting retinal changes has improved since the initial guidelines were set. The new guidelines recommend eye doctors perform a comprehensive eye exam, including the following The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool.