B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Abruptly stopping plaquenil Medicine used for malaria hydroxychloroquine Chloroquine tablet prescription Oct 22, 2019 The risk may also be higher with some doses of Plaquenil hydroxychloroquine, if you use Plaquenil hydroxychloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight changes like blurred or foggy eyesight, trouble focusing or reading, or trouble seeing in dim light. Applies to hydroxychloroquine oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Bruising on shin from plaquenil Rheumatoid Arthritis Skin Problems Nodules, Rashes, and More, Hydroxychloroquine Side Effects Common, Severe, Long Term. Order aralen phosphateDiphenhydramine interaction with plaquenil Importance Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. Hydroxychloroquine-Induced Pigmentation in Patients With.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Skin Pigmentation with Hydroxychloroquine Plaquenil.. It may initially help a bruise from worsening, but it rarely has a benefit on a bruise after the first 24 hours,” Dr. Friedler says. “After that time, heat can sometimes help the bruise. Redness, bruising, itching, or swelling where the injection was given. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects.