I'm interested to eventually see the mechanism by which COVID19 is causing pneumonia. It would be an additional effect as well as this would not play a role in cell culture. My guess for the pneumonia is the cytokine induction induced by viral RNA or other innate immune signals. Plaquenil and sjogrens syndrome Is hydroxychloroquine sulfate a sulfa drug Chloroquine, synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be The search for the cure of Coronavirus has been on for some time now, and Chinese experts, based on the result of clinical trials, have confirmed that chloroquine phosphate, has a certain curative effect on the novel coronavirus disease COVID-19. Chloroquine, an antimalaria drug of the group of 4-aminoquinolines, works well and effectively as a schizonticidal drug against the erythrocytic forms of all types of plasmodia. Today though, almost all pathogens of the potentially lethal malaria tropica have become resistant to this rather well tolerated, and for many decades, useful medication. There might be a source for coronavirus-induced cell death out there ... Another option is induced cell death by virus infection. Chloroquine phosphate lethal Massive chloroquine overdose--a survivor., Chloroquine confirmed as anti-viral drug for Coronavirus Plaquenil guidelines aaoUsing pei vs chloroquineChloroquine for vivax malaria Chloroquine, an anti-malaria drug that President Trump fast-tracked for clinical testing this week in the fight against coronavirus, can be deadly for kids, according to an Oklahoma family who said Potential coronavirus drug chloroquine could be deadly to kids. Chloroquine - an overview ScienceDirect Topics. Chloroquine - FDA prescribing information, side effects and uses. Antiviral activity of chloroquine against a lethal HCoV-OC43 infection in newborn C57BL/6 mice. We investigated whether chloroquine could prevent death in newborn mice as a result of infection with HCoV-OC43. C57BL/6 mice were selected in view of their susceptibility to HCoV-OC43 14, 15. Pregnant mice were left untreated or treated. Chloroquine phosphate, an old drug for the treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. What threatened to be a very dark period for the world, both medically and economically, has finally seen a ray of light. Recent reports state that anti-malarial drug chloroquine phosphate could play a key role in battling the deadly novel coronavirus, now called Covid-19.