Woman in grey hydroxychloroquine-induced hyperpigmentation

Discussion in 'Canadian Pharcharmy Online' started by gurasus, 05-Mar-2020.

  1. fillin XenForo Moderator

    Woman in grey hydroxychloroquine-induced hyperpigmentation


    B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions.

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    Pigmentation is an important factor in determining drug incorporation into hair. Results from 1211 samples of hair from healthy subjects 577 men and 634 women show that tryptophan levels are significantly higher in males 37.83±3.45 μg/g dry hair than in females 26.62±2.40 μg/g hair. An African American woman, aged 50 years, presents with painless “bruises” on her leg. She first noticed bruises on both legs a year ago and reports that they have since become larger. An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B.

    B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100).

    Woman in grey hydroxychloroquine-induced hyperpigmentation

    Acquired Hemochromatosis with Pronounced Pigment Deposition., Painless, bruise-like hyperpigmentation on a woman with.

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  6. Woman With Blue-Gray Palate and Nail Beds Susan Chrostowski, MS, RN, ANP, Barbara Gray, PhD, RN, CPNP, Peggy Mancuso, PhD, RN, CNM, CNE GRANDROUNDS Susan Chrostowski practices at Rheumatology Associates in Dallas. Bar-bara Gray is an Associate Professor and Peggy Mancuso is a Professor at Texas Woman’s University in Dallas. FIGURE 1

    • Woman With Blue-Gray Palate and Nail Beds.
    • Hydroxychloroquine induced cutaneous pigmentation a unique..
    • Updated recommendations on the use of hydroxychloroquine in..

    Background/Purpose To describe the clinical features and outcome of hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus SLE. Method This was a retrospective, monocentric SLE clinic, Pitié-Salpêtrière, Paris study of SLE patients with pigmented lesions considered to be related to hydroxychloroquine HCQ. Boyd reported the case of a 72-year-old woman with a slowly expanding lesion of her right cheek that measured 3 cm; it displayed variable pigmentation ranging from brown to gray to black. Her ANA was positive at 0 and the biopsy confirmed lupus. He then performed a retrospective analysis of 11 similar cases 9 women, 2 men, average age 68. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia,

     
  7. tonik1 Moderator

    If you have psoriatic arthritis and experience persistent pain and fatigue, you may need to be screened for a chronic disorder known as fibromyalgia. Does Medical Marijuana Work for Psoriatic Arthritis? How effective is Plaquenil for Psoriatic arthritis by. Fibromyalgia vs. psoriatic arthritis, differences in.
     
  8. NHBFan Moderator

    Plaquenil & Your Eyes The most important affect of Plaquenil on your eye is to damage the retina at the back of your eye. Fortunately, this is very uncommon and generally only occurs in patients on high doses or patients with bad kidney function.

    Hydroxychloroquine Side Effects, Dosage, Uses, and More
     
  9. svetik529 Well-Known Member

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