In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Chloroquine volume of distribution Chloroquine trade name in pakistan Plaquenil biologic User Reviews for Hydroxychloroquine to treat Sjogren's Syndrome. Also known as. The other immune drugs have scary side effects almost worth waiting for a flare and dealing with steroids then the side effects of the immune suppressants and plaquinel name brand and generic not worth the constant feeling of vomiting there has to be something. Importance Primary Sjögren syndrome is a systemic autoimmune disease characterized by mouth and eye dryness, pain, and fatigue. Hydroxychloroquine is the most frequently prescribed immunosuppressant for the syndrome. Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil and hyperpigmentation sjogren's Hydroxychloroquine-Associated Hyperpigmentation Mimicking., Hydroxychloroquine for Sjögren Syndrome Symptoms Delayed allergic reaction to plaquenilPlaquenil 200mg tablets hydroxychloroquine sulphate Hydroxychloroquine has numerous adverse effects, necessitating vigilance on the part of the prescriber. Most commonly reported are retinopathy, hyperpigmentation, myopathy, and skin reactions. 1. Retinopathy Hydroxychloroquine An old drug with new relevance Cleveland Clinic.. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Plaquenil Side Effects Common, Severe, Long Term -. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. I have a terribly advanced case of SS. My personal experience with Plaquenil, which I took for four years starting at diagnosis, was that it did nothing to improve any aspect of the disease. The progression of SS, if anything, amplified during this time. I'm also left with permanent hyperpigmentation on my forearms. I apologize; That's a crummy. I saw a rheumatologist finally today. She prescribed Plaquenil and drew 12 vials of blood to check my clotting factors and test for lupus, as well as a urine test to check my kidneys she said. My concern is if this med will cause me to gain weight. Since my TIÀ 1/03/16 I have gained almost 20 pounds and don't want to do anything to increase that.