It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil and prednisone for rheumatoid arthritis Plaquenil and ankylosing spondylitis Is it safe to take plaquenil and tramadol together Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Hydroxychloroquine Plaquenil is a disease-modifying anti-rheumatic drug DMARD indicated approved for use for the treatment of RA. How does hydroxychloroquine work? Missy Leavell This also hurts the ones like me I have rheumatoid arthritis & can’t function without pain control. How many times can I get it? I've heard that plaquenil does help w/ fatigue as well as the pain? Is this true. Right now I am not on any Dmards but when I push myself more than like 4 hrs a day out of the house running errands, etc I totally crash w/ fatigue and pain. I take tramadol and NSAIDs but wondering if I need. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil vs nsaids for arthritis MTX vs Plaquenil • Johns Hopkins Arthritis Center, How Does Plaquenil Work For Rheumatoid Arthritis Hydroxychloroquine dosage for osteoarthritis Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Azulfidine Sulfasalazine is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis. Compare Plaquenil vs Sulfasalazine -. Plaquenil for fatigue and pain DailyStrength. Treating Rheumatoid Arthritis DMARDs vs. Biologics.. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. The only thing I'm on right now is Sulindac is a NSAID and the MTX and I am much better than I was the Sulindac seems to be great for me. However the follow-up yesterday with the RA doc said that I still have active RA, which I can feel in hands and feet but compared to where I was some weeks ago this is very good. I am still on 7 mg of Prednisone daily, but am trying to wean slowly. I still have flares now and then, but work full time. I have not had problematic side effects from the Plaquenil or MTX, but the steroids caused weight gain and some hair loss besides what was caused by the arthritis.