In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Can i use of hydroxychloroquine with sulfa allergy Hydroxychloroquine 200 mg I am on Plaquenil for RA and Sjogrens syndrome. I have extremely dry eyes and sometimes eye irritation which is caused from the Sjogrens syndrome which often goes hand and hand with RA. Apparently the plaquenil is supposed to help with the Sjogrens but i have yet to see an improvment in my dry eyes, it's infact gotten worse. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. Get medical help right away if you have any very serious side effects, including chest pain, fast/irregular heartbeat, severe dizziness, fainting, seizures. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil side effects eye pain Side effects of Plaquenil Other Drugs discussions., Hydroxychloroquine Plaquenil How to manage inflammation after coming off hydroxychloroquineWhat company makes plaquenilCost of chloroquine malaria tabletsPlaquenil effect on thyroid Lower back or side pain. noisy breathing. painful or difficult urination. red irritated eyes. red skin lesions, often with a purple center. severe mood or mental changes. sore throat sores, ulcers, or white spots on the lips or in the mouth. sticking out of the tongue. stomach pain. swelling of the feet or lower legs. swollen or painful glands Plaquenil Side Effects - GoodRx. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Rx Side Effects New Plaquenil Guidelines and More.. Sep 13, 2019 For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or. Call your doctor immediately or get emergency medical help if you experience any of the following serious side effects Any vision problems, such as reading difficulties, sensitivity to light, seeing light flashes or streaks, blurred distance vision, or other issues Hearing problems.