The main finding in scleroderma is thickening and tightening of the skin and inflammation and scarring of many body parts, leading to problems in the lungs, kidneys, heart, intestinal system and other areas. Twins and family members of those with scleroderma or other autoimmune connective tissue diseases, such as lupus, may have a slightly higher risk of getting scleroderma. There is still no cure for scleroderma, but effective treatments for some forms of the disease are available. Children can also develop scleroderma, but the disease is different in children than in adults. Plaquenil and kidneys Plaquenil and metoprolol How much does aralen cost The incidence of CREST syndrome is not known. The incidence of systemic sclerosis in the general population is in the range of approximately 2-71,000,000 with geographical differences. All ethnicities can be affected. Females are affected two to four times more often than males. + + Long term ratings 3/5. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Systemic sclerosis scleroderma and for what kind of people. The study is created by eHealthMe from 11 Plaquenil users and is updated continuously. eHealthMe has been monitoring drugs and supplements since 2008. Jan 22, 2016 I was 55 when diagnosed with "CREST" in 2000 & started on Plaquenil & a since withdrawn NSAID. My early symptoms in addition to abnormal labs were severe fatigue, joint pain mainly in lower body - legs & hips, reflux & Raynauds. A great deal of research is also underway to find better treatments for scleroderma and, hopefully, someday a cure. Although the underlying cause is unknown, promising research is shedding light on the relationship between the immune system and scleroderma. Hydroxychloroquine for crest syndrome Scleroderma Guide Causes, Symptoms and Treatment Options, How effective is Plaquenil for Systemic sclerosis. Con que puedo tomar el plaquenil para no engodarHydroxychloroquine and hashimoto's diseasePlaquenil vision side effectsAct or chloroquine malariaPlaquenil how to buy CREST syndrome, also known as limited scleroderma, is a widespread connective tissue disease characterized by changes in the skin, blood vessels, skeletal muscles, and internal organs. The symptoms involved in CREST syndrome are associated with the generalized form of the disease systemic sclerosis scleroderma. CREST is an acronym for the. CREST syndrome Genetic and Rare Diseases Information Center GARD.. Just Diagnosed with Crest Syndrome & Prescribed Plaquenil.. Plaquenil/ hydroxychloroquine Phoenix Rising ME / CFS Forums. I've had a CREST diagnosis for 10 years now and she mentioned at our last visit that she feels I don't have that, but have Sjogren's instead. Mind you I have no dry eyes, mouth, or anything else. And I consistently test positive with the anticentromere pattern. And I have the R, S, and T of CREST. CREST syndrome, also known as the limited cutaneous form of systemic sclerosis lcSSc, is a multisystem connective tissue acronym "CREST" refers to the five main features calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. This section of the Scleroderma FAQ is focused on standard treatment approaches that are designed either to target the overall disease process or to modify the disease in a way that can potentially improve more than one symptom, for example, bosentan Tracleer for skin ulcers and PAH.