The toxicities can be grouped into categories such as pigmentary retinopathies, crystalline retinopathies, retinal vasculopathies, and retinopathies characterized by retinal edema or folds. Here we present a case of topiramate (Topamax, Ortho-Mc Neil Neurologics) causing transient angle closure and retinal folds. Can plaquenil and metoprolol tartrate be taken together Rituxan interac with plaquenil Baseline fundus photographs and FA are helpful in patients with pre-existing macular pigmentary changes. Patients are classified as being at a higher risk of developing toxicity if they exceed 3 mg/kg/day of chloroquine, or 6.5 mg/kg/day of hydroxychloroquine calculated based on ideal body weight. Retinal Screening for Hydroxychloroquine Plaquenil Toxicity Medications used to treat various systemic conditions can have ocular side effects. In particular, chloroquine and hydroxychloroquine Plaquenil are two such medications, with the potential for retinal toxicity. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. A 26-year-old woman reported to the emergency room with a chief complaint of sudden, painless loss of vision in both eyes. We follow with a review of the literature regarding topiramate toxicity, as well as a brief review of the other major categories of pharmacologic retinal toxicity. Retinal plaquenil toxicity Retina Today - Imaging in Hydroxychloroquine Toxicity., Retinal Screening for Hydroxychloroquine Plaquenil Toxicity Phototherapy and plaquenil combinationPlaquenil did not work for meStopping plaquenil effects Nov 01, 2015 H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible. Retinal Physician - Hydroxychloroquine Maculopathy An Update.. Rx Side Effects New Plaquenil Guidelines and More - American.. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. Chloroquine and hydroxychloroquine belong to the quinolone family. Although their therapeutic and toxic doses differ, they are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity. Initially, chloroquine was given for malaria prophylaxis and treatment. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible. Symptoms of Plaquenil toxicity are similar to other macular problems and may include Decreased fine vision or difficulty reading. Changes in Color vision. Missing Spots or shadows near the center of the vision.