Baseline reading for plaquenil therapy

Discussion in 'Canada Drug' started by Zauberg, 23-Feb-2020.

  1. SBI User

    Baseline reading for plaquenil therapy


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    The issues are reading, color and night vision. Patient 2 69 year old male presents with a history of long term plaquenil use. Diagnosed with RA at age 19 now has almost no use of his hands. Has had 10 surgeries mostly joint replacements, stopped all drugs last year after a life threatening infection now starting back on therapy. I have lichen planopilaris and the doctor is recommending treatment with Plaquenil. Upon reading the side effects - Answered by a verified Dermatologist. I have lichen planopilaris and the doctor is recommending treatment with Plaquenil. Upon reading the side effects online, it seems that the drug is quite toxic. Also the baseline. Baseline Screening. But it was for alleged Plaquenil related eye toxicity, and believe me, attornies will grab any guideline they can as "Standard-of-Care" if it suits their case. And lucky for me, my lawsuit was dropped after the plaintiff was seen reading the newspaper and his cell phone in the waiting room of his lawyer's office.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Baseline reading for plaquenil therapy

    Recommendations on Screening for Chloroquine and., I have lichen planopilaris and the doctor is recommending.

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  5. Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said.

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    The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and If there is a favorable response, therapy is tapered to 50mg every 2 weeks for 3 months, then every 3 weeks for 3 months and then finally to a maintenance monthly dose. No response after a total of 1g should be considered a treatment failure. Monthly gold should be continued indefinitely. Because early toxicity changes can be revealed on SD-OCT, it is prudent to perform a baseline screening of patients taking Plaquenil. Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended.

     
  6. El_Gato Moderator

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Are you taking hydroxychloroquine Plaquenil? How often do. How to Succeed in Plaquenil Screenings RCOphth guideline Hydroxychloroquine and Chloroquine.
     
  7. agebages Guest

    PLAQUENIL" Rheumatoid Arthritis Community - Support Group It will help with mild/moderate joint pain, but is usually given with other drugs for better pain relief. It works well on the more systemic side effects of RA e.g. pericarditis, pleuritis.

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