It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine phosphate doctors foster and smith Fundus in chloroquine Rheumatoid arthritis chloroquine Side effects of Plaquenil and prednisone that are similar include nausea, vomiting, or headache. Side effects of Plaquenil that are different from prednisone include stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash. SIDE EFFECTS Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Side effects of plaquenil withdrawal Can Plaquenil cause Withdrawal Symptoms? - Page 3, HYDROXYCHLOROQUINE - ORAL Plaquenil side effects. Hydroxychloroquine with alcoholWhat does plaquenil do to your eyesPlaquenil maculopathy fafPlaquenil macular degenerationPrecaution of chloroquine I believe it is like any other drug, side effects can and do happen, but they are very individualized. I would like to be able to keep taking plaquenil, I just want to reduce my dose by half. I had no idea it was going to so profoundly impact me, and I guess I feel like I need to understand why. Let me tell you what weaning down from Plaquenil is like.. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Hi I have Lupus and have been on Paquenil for for about yearsMy eye Doctor says the left eye is showing toxins from the drug are starting to cause damage and I need to stop taking it.