We were much later told that the Plaquenil had "lowered his tolerance to infection, as it is also an immuno-suppressant." In essence, the medicine allowed the viral infection to cross the barrier between his brain and blood/lungs. His/our question is as to whether he can or should EVER go back on the medication and risk exposure to further illnesses if it is true that Plaquenil or the generic for is, in fact, an immuno-suppressant and presents a serious health risk for him? Chloroquine selleckchem Metabolism of chloroquine Plaquenil arava Wow, I hate to hear that you had to stop taking plaquenil. It's such a wonder drug. What does your rheumy suggest? Not knowing what your dx is, I don't know what to tell you. Since you're taking Enbrel and MTX, I suppose you have RA and I can't imagine having that and not being able to take plaquenil. Rheumatoid arthritis RA, the most common form of inflammatory arthritis, can lead to significant pain, disability, and deformity, and is a multisystem autoimmune disorder. The hallmark of this disease, erosive joint destruction, results from unchecked synovial inflammation, which can damage articular cartilage and bone, with resultant loss of. One of the problems with Plaquenil is that because it's so slow to act, the improvements are also slow and subtle. So most people don't realize that they've improved until they STOP taking it. I've been on it twice, along with Atabrine another antimalarial. In my case, it never worked so I didn't notice a change. We've been told that his 'count' (900 cells per 1,000) was the highest infection level in the spinal fluid that the doctors had ever seen. All the patients they'd encountered w/lower levels had died. (He was never told of that risk when he was put on the medication.) Added : What I failed to mention (above) is that he almost died in April when this happened. Stop antibodies drug plaquenil Hydroxychloroquine plaquenil withdrawl? - LUPUS UK, Perioperative Management of Medications Used in the Treatment. Chloroquine selleckCan plaquenil cause low blood sugarNeostigmine chloroquine phosphateHow effective is chloroquineChloroquine er derived vaculation Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil Uses, Dosage & Side Effects -. Stopping plaquenil. DailyStrength. Stopping Plaquenil and Cellcept when on Antibiotics. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. When phenothiazine medications, certain beta blockers, or certain parasite medicines are taken together with Plaquenil, interactions can occur that may affect the drug levels in your blood. This could increase your risk for side effects or decrease the effectiveness of the medicines. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.